Stereotactic targeting of the ventrointermediate nucleus of the thalamus by direct visualization with high-field MRI

Roberto Spiegelmann*, Ouzi Nissim, Diana Daniels, Aharon Ocherashvilli, Yael Mardor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the ability of high-field MRI to consistently produce high-resolution, anatomical images of the thalamic ventrointermediate nucleus (Vim) suitable for stereotactic targeting. Methods: MR images of the thalamus of patients treated for essential tremor were acquired prior to treatment using a 3-tesla MR system. Similar images were acquired in 6 volunteers using, for comparison, both a 1.5-tesla and a 3.0-tesla system. Results: The thalamic Vim was clearly and consistently delineated on the 3-tesla images. These images were successfully used for target localization in essential tremor patients. In the volunteers data, images acquired using the 1.5-tesla system were inferior to those acquired using the 3-tesla system, lacking the ability to consistently provide reliably defined borders of the Vim. Conclusion: 3-tesla MRI can provide high-quality depiction of the Vim, potentially enabling accurate treatment planning by direct visualization and definition of the targeted Vim.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalStereotactic and Functional Neurosurgery
Volume84
Issue number1
DOIs
StatePublished - Jun 2006
Externally publishedYes

Keywords

  • High-field MRI
  • Surgery for tremor
  • Ventrointermediate nucleus

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