Statistical identification of delayed repolarization: Applicability in long QT syndrome (LQTS) population

S. Gottlieb; A. J. Moss; W. J. Hall; S. Choi; F. Badilini; M. L. Andrews; E. H. Locati; J. L. Robinson

Statistical identification of delayed repolarization: Applicability in long QT syndrome (LQTS) population

S. Gottlieb, A. J. Moss, W. J. Hall, S. Choi, F. Badilini, M. L. Andrews, E. H. Locati, J. L. Robinson

Clinical Departments

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The objectives of this study were: to establish normal standards for QT intervals, based on a large normal population, using high-quality digitized electrocardiogram recordings, and a statistical probabilistic approach adjusting for heart-rate, age, and gender, and to apply this approach to the LQTS international registry. Based on digitized electrocardiogram recordings and multiregression methods adjusting the QT interval for RR interval, age, and gender, in normal population (N = 578) a measurement called adjusted QT (QTa) was determined. QTa is expressed in normal population standard deviation units, and in percentiles (%QTa). The QTa was applied to the LQTS multicenter registry (N = 2000), treating probands (N = 326), and family members (N = 1674) separately.

Original language	English
Title of host publication	Computers in Cardiology
Publisher	Publ by IEEE
Pages	297-300
Number of pages	4
ISBN (Print)	081862485X
State	Published - 1992
Event	Proceedings of the 18th Annual Conference on Computers in Cardiology - Venice, Italy Duration: 23 Sep 1991 → 26 Sep 1991

Publication series

Name	Computers in Cardiology
ISSN (Print)	0276-6574

Conference

Conference	Proceedings of the 18th Annual Conference on Computers in Cardiology
City	Venice, Italy
Period	23/09/91 → 26/09/91

Cite this

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title = "Statistical identification of delayed repolarization: Applicability in long QT syndrome (LQTS) population",

abstract = "The objectives of this study were: to establish normal standards for QT intervals, based on a large normal population, using high-quality digitized electrocardiogram recordings, and a statistical probabilistic approach adjusting for heart-rate, age, and gender, and to apply this approach to the LQTS international registry. Based on digitized electrocardiogram recordings and multiregression methods adjusting the QT interval for RR interval, age, and gender, in normal population (N = 578) a measurement called adjusted QT (QTa) was determined. QTa is expressed in normal population standard deviation units, and in percentiles (%QTa). The QTa was applied to the LQTS multicenter registry (N = 2000), treating probands (N = 326), and family members (N = 1674) separately.",

author = "S. Gottlieb and Moss, {A. J.} and Hall, {W. J.} and S. Choi and F. Badilini and Andrews, {M. L.} and Locati, {E. H.} and Robinson, {J. L.}",

year = "1992",

language = "אנגלית",

isbn = "081862485X",

series = "Computers in Cardiology",

publisher = "Publ by IEEE",

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booktitle = "Computers in Cardiology",

note = "null ; Conference date: 23-09-1991 Through 26-09-1991",

}

Gottlieb, S, Moss, AJ, Hall, WJ, Choi, S, Badilini, F, Andrews, ML, Locati, EH & Robinson, JL 1992, Statistical identification of delayed repolarization: Applicability in long QT syndrome (LQTS) population. in Computers in Cardiology. Computers in Cardiology, Publ by IEEE, pp. 297-300, Proceedings of the 18th Annual Conference on Computers in Cardiology, Venice, Italy, 23/09/91.

Statistical identification of delayed repolarization : Applicability in long QT syndrome (LQTS) population. / Gottlieb, S.; Moss, A. J.; Hall, W. J.; Choi, S.; Badilini, F.; Andrews, M. L.; Locati, E. H.; Robinson, J. L.

Computers in Cardiology. Publ by IEEE, 1992. p. 297-300 (Computers in Cardiology).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Statistical identification of delayed repolarization

AU - Gottlieb, S.

AU - Moss, A. J.

AU - Hall, W. J.

AU - Choi, S.

AU - Badilini, F.

AU - Andrews, M. L.

AU - Locati, E. H.

AU - Robinson, J. L.

PY - 1992

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AB - The objectives of this study were: to establish normal standards for QT intervals, based on a large normal population, using high-quality digitized electrocardiogram recordings, and a statistical probabilistic approach adjusting for heart-rate, age, and gender, and to apply this approach to the LQTS international registry. Based on digitized electrocardiogram recordings and multiregression methods adjusting the QT interval for RR interval, age, and gender, in normal population (N = 578) a measurement called adjusted QT (QTa) was determined. QTa is expressed in normal population standard deviation units, and in percentiles (%QTa). The QTa was applied to the LQTS multicenter registry (N = 2000), treating probands (N = 326), and family members (N = 1674) separately.

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BT - Computers in Cardiology

PB - Publ by IEEE

Y2 - 23 September 1991 through 26 September 1991

ER -

Statistical identification of delayed repolarization: Applicability in long QT syndrome (LQTS) population

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