Statin Use is Associated with Better Cognitive Function in Elderly with Type 2 Diabetes

Anthony D. Heymann*, Ramit Ravona-Springerc, Erin L. Moshier, James Godbold, Michal Schnaider Beeri

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The pleiotropic contribution of statins on cognition is uncertain. From 840 patients in the cohort from the Israel Diabetes and Cognitive Decline Study, we identified 61 non-statin users and compared them with 45 patients who had used statins at least 90% of the time. Analysis of covariance was performed to compare mean cognitive z-scores between statin users and non-users while adjusting for socio-demographic, diabetes-related, and cardiovascular covariates which included change in cholesterol by year. Overall cognition, memory, and executive function was found to be significantly better in statin users (p < 0.0008). This suggests a positive effect of statins on cognitive function of type 2 diabetes patients that is independent of cholesterol levels.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalJournal of Alzheimer's Disease
Issue number1
StatePublished - 2015


  • All cognitive disorders/dementia
  • Alzheimer's disease
  • Case control studies
  • Diabetes


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