State-of-the-art fertility preservation in children and adolescents undergoing haematopoietic stem cell transplantation: A report on the expert meeting of the Paediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) in Baden, Austria, 29-30 September 2015

J. H. Dalle*, G. Lucchini, A. Balduzzi, M. Ifversen, K. Jahnukainen, K. T. MacKlon, A. Ahler, A. Jarisch, M. Ansari, E. Beohou, D. Bresters, S. Corbacioglu, A. Dalissier, C. DIaz De Heredia Rubio, T. DIesch, B. Gibson, T. Klingebiel, A. Lankester, A. Lawitschka, R. MoffatC. Peters, C. Poirot, N. Saenger, P. Sedlacek, E. Trigoso, K. Vettenranta, J. Wachowiak, A. Willasch, M. Von Wolff, I. Yaniv, A. Yesilipek, P. Bader

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Nowadays, allogeneic haematopoietic stem cell transplantation (allo-HSCT) is a well-established treatment procedure and often the only cure for many patients with malignant and non-malignant diseases. Decrease in short-term complications has substantially contributed to increased survival. Therefore long-term sequelae are reaching the focus of patient care. One of the most important risks of stem cell transplant survivors is infertility. As well as in the field of allo-HSCT also the field of reproductive medicine has achieved substantial advances to offer potential options for fertility preservation in both boys and girls. Access to these procedures as well as their financing differs significantly throughout Europe. As all European children and adolescents should have the same possibility, the Paediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation organised an expert meeting in September 2015. This manuscript describes the recommendations for the diagnosis and pre-emptive procedures that should be offered to all children and adolescents in Europe who have to undergo an allo-HSCT.

Original languageEnglish
Pages (from-to)1029-1035
Number of pages7
JournalBone Marrow Transplantation
Volume52
Issue number7
DOIs
StatePublished - 1 Jul 2017

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