Spontaneous regression of hodgkin lymphoma: Case report and review of the literature

Oren Pasvolsky*, Tamar Berger, Hanna Bernstine, Lucille Hayman, Pia Raanani, Liat Vidal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Spontaneous regression of Hodgkin lymphoma (HL) is a rare event. We describe a 32-year-old woman with spontaneous regression of HL and review the literature. The patient presented with cervical lymphadenopathy and was diagnosed with stage IIA classical HL. The patient refused to receive any treatment for her disease. Positron emission tomography/computed tomography carried out 2 years later showed complete regression of the lymphadenopathy, without pathological uptake of fluorodeoxyglucose. At the last follow-up, 3.5 years after the initial presentation, the patient is with no evidence of disease. During workup for the HL, concomitant papillary thyroid carcinoma was diagnosed, for which the patient refused treatment as well. The thyroid malignancy has remained stable throughout the follow-up.

Original languageEnglish
Pages (from-to)14-18
Number of pages5
JournalActa Haematologica
Issue number1
StatePublished - 1 Jan 2019


  • Hodgkin lymphoma
  • Positron emission tomography in Hodgkin/non-Hodgkin lymphoma
  • Spontaneous regression


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