Spinal Cord MRI in Multiple Sclerosis

Alexandra Muccilli, Estelle Seyman, Jiwon Oh*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Spinal cord (SC) MRI in multiple sclerosis (MS) has significant usefulness in clinical and investigational settings. Conventional MRI of the SC is used in clinical practice, because it has both diagnostic and prognostic value. A number of advanced, quantitative SC MRI measures that assess the structural and functional integrity of the SC have been evaluated in investigational settings. These techniques have collectively demonstrated usefulness in providing insight into microstructural and functional changes relevant to disability in MS. With further development, these techniques may be useful in clinical trial settings as biomarkers of neurodegeneration and protection, and in day-to-day clinical practice.

Original languageEnglish
Pages (from-to)35-57
Number of pages23
JournalNeurologic Clinics
Issue number1
StatePublished - Feb 2018
Externally publishedYes


  • Clinical usefulness
  • MRI
  • Multiple sclerosis
  • Prediction
  • Quantitative techniques
  • Spinal cord


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