Spinal Canal Involvement in Peripheral Neuroblastic Tumors

Shifra Ash; Stefania Sorrentino; Kathelijne Kraal; Bruno De Bernardi

doi:10.1007/978-3-030-18396-7_9

Spinal Canal Involvement in Peripheral Neuroblastic Tumors

Shifra Ash, Stefania Sorrentino, Kathelijne Kraal, Bruno De Bernardi^*

^*Corresponding author for this work

Pediatrics

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Approximately 15% of children with peripheral neuroblastic tumors (PNTs) present with spinal canal involvement (SCI) by the tumor, and half of them develop important related symptoms. Symptomatic SCI requires prompt treatment: chemotherapy, neurosurgical intervention and radiation therapy may all be effective, but there is no consent on which should be given first in the different clinical presentations. The literature regarding PNT with SCI does not provide convincing guidelines, thus encouraging the establishment of a specific International Registry to provide data that could lead to the definition of a suitable therapeutic and follow-up algorithm.

Original language	English
Title of host publication	Neuroblastoma
Subtitle of host publication	Clinical and Surgical Management
Publisher	Springer International Publishing
Pages	173-189
Number of pages	17
ISBN (Electronic)	9783030183967
ISBN (Print)	9783030183950
DOIs	https://doi.org/10.1007/978-3-030-18396-7_9
State	Published - 1 Jan 2019

Keywords

Chemotherapy
Epidural compression
Imaging of SCI
Laminectomy and laminotomy
Late sequelae
Multidisciplinary follow-up
Multidisciplinary therapeutic approach
Neuroblastoma
Peripheral neuroblastic tumors
Radiation therapy
SCI at birth and in the neonate
Spinal canal involvement (SCI)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-030-18396-7_9

Cite this

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abstract = "Approximately 15% of children with peripheral neuroblastic tumors (PNTs) present with spinal canal involvement (SCI) by the tumor, and half of them develop important related symptoms. Symptomatic SCI requires prompt treatment: chemotherapy, neurosurgical intervention and radiation therapy may all be effective, but there is no consent on which should be given first in the different clinical presentations. The literature regarding PNT with SCI does not provide convincing guidelines, thus encouraging the establishment of a specific International Registry to provide data that could lead to the definition of a suitable therapeutic and follow-up algorithm.",

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AU - Sorrentino, Stefania

AU - Kraal, Kathelijne

AU - De Bernardi, Bruno

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KW - Late sequelae

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Spinal Canal Involvement in Peripheral Neuroblastic Tumors

Abstract

Keywords

UN SDGs

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