Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients

Keyphrases

• Smokers 100%
• Non-smokers 100%
• Lung Cancer 100%
• Germline mutation 100%
• Non-small Cell Lung Cancer Patients 100%
• Smoking Status 60%
• Germ Cells 60%
• TP53 mutation 60%
• Recurring 40%
• R337H 40%
• Major Risk Factors 20%
• Same Patient 20%
• Brazil 20%
• Whole Exome Sequencing 20%
• Mutational Profile 20%
• Sanger Sequencing 20%
• Missense Variants 20%
• Genetic Factors 20%
• Never-smokers 20%
• Cancer Mortality 20%
• TP53 Gene 20%
• Cancer Cases 20%
• Tumor DNA 20%
• Pathogenic mutations 20%
• Non-small Cell Lung Cancer (NSCLC) 20%
• Cancer Causes 20%
• Illumina HiSeq 2000 20%
• Novel Sequences 20%
• Sequence Variants 20%
• Cancer Predisposition 20%
• Cancer Pathogenesis 20%
• Mendel 20%
• RAD52 20%
• Aurora Kinase A (AURKA) 20%
• Multiple Cancer Types 20%
• Germline DNA 20%
• Germline Variants 20%
• Smoking Patient 20%
• Mutation Sequence 20%
• Ingenuity 20%
• THBS1 20%
• ATAD2 20%
• CDC6 20%
• PLCD1 20%
• PTPRD 20%

Biochemistry, Genetics and Molecular Biology

• Germline 100%
• Germ Cell 100%
• Germline Mutation 100%
• Exome Sequencing 20%
• Missense 20%
• Genetic Determinism 20%
• RAD52 20%
• Protein Tyrosine Phosphatase Receptor Delta 20%
• Dideoxynucleotide Sequencing 20%