"Special" intraocular lens designs: Why do they sometimes fail?

Irmingard M. Neuhann, Guy Kleinmann, David J. Apple

Research output: Contribution to journalReview articlepeer-review


A variety of new "special" intraocular lens models to optimize the visual performance after cataract surgery have been introduced. The majority of these new intraocular lens designs require a good centration within the capsular bag and/or capsular elasticity. Today, the main post-operative complications after cataract surgery still arise from retained lens epithelial cells within the capsular bag, resulting mainly in anterior and posterior capsule opacification. Some special intraocular lenses are not designed to be effective against proliferating lens epithelial cells. Although lens epithelial cells can never be completely removed from the capsular bag, surgical quality is a major factor for success or failure of these intraocular lens designs.

Original languageEnglish
Pages (from-to)53-60
Number of pages8
JournalComprehensive Ophthalmology Update
Issue number2
StatePublished - Mar 2006
Externally publishedYes


  • Anterior capsule opacification
  • Cataract surgery
  • Intraocular lenses
  • Lens epithelial cells
  • Posterior capsule opacification


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