Some indications for inverse DNA duplication

Ruth Nussinov*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Calculations of the distribution of single nucleotides and doublets in many of the recently published sequences are consistent with the suggestion that some DNA has evolved through inverse ligation of duplicated sequences. We thus propose that this mechanism which yields sequence variation has been utilized in addition to the well known "regular" sequence duplication.

Original languageEnglish
Pages (from-to)783-791
Number of pages9
JournalJournal of Theoretical Biology
Issue number4
StatePublished - 21 Apr 1982
Externally publishedYes


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