Somatostatin therapy ameliorates chronic and refractory gastrointestinal bleeding caused by diffuse angiodysplasia in a patient on anticoagulation therapy

Miry Blich*, O. Fruchter, S. Edelstein, Y. Edoute

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We present a patient receiving chronic anticoagulant treatment with recurrent and intractable gastrointestinal bleeding due to diffuse angiodysplasia. Following failure of previous medical and surgical treatment, and in light of the patient's need for chronic anticoagulation due to mechanical heart valve, she was treated with somatostatin analogue, octreotide s.c. 100 μg on alternate days for 28 months. Treatment significantly decreased the occurrence of bleeding episodes, the need for hospitalization and blood transfusion requirements despite continued anticoagulant therapy. Octreotide treatment should be considered in patients with refractory gastrointestinal bleeding due to angiodysplasia in particular in those who need anticoagulant treatment.

Original languageEnglish
Pages (from-to)801-803
Number of pages3
JournalScandinavian Journal of Gastroenterology
Volume38
Issue number7
DOIs
StatePublished - 1 Jul 2003
Externally publishedYes

Keywords

  • Anticoagulation therapy
  • Diffuse angiodysplasia
  • Somatostatin therapy

Fingerprint

Dive into the research topics of 'Somatostatin therapy ameliorates chronic and refractory gastrointestinal bleeding caused by diffuse angiodysplasia in a patient on anticoagulation therapy'. Together they form a unique fingerprint.

Cite this