TY - JOUR
T1 - Somatostatin therapy ameliorates chronic and refractory gastrointestinal bleeding caused by diffuse angiodysplasia in a patient on anticoagulation therapy
AU - Blich, Miry
AU - Fruchter, O.
AU - Edelstein, S.
AU - Edoute, Y.
PY - 2003/7/1
Y1 - 2003/7/1
N2 - We present a patient receiving chronic anticoagulant treatment with recurrent and intractable gastrointestinal bleeding due to diffuse angiodysplasia. Following failure of previous medical and surgical treatment, and in light of the patient's need for chronic anticoagulation due to mechanical heart valve, she was treated with somatostatin analogue, octreotide s.c. 100 μg on alternate days for 28 months. Treatment significantly decreased the occurrence of bleeding episodes, the need for hospitalization and blood transfusion requirements despite continued anticoagulant therapy. Octreotide treatment should be considered in patients with refractory gastrointestinal bleeding due to angiodysplasia in particular in those who need anticoagulant treatment.
AB - We present a patient receiving chronic anticoagulant treatment with recurrent and intractable gastrointestinal bleeding due to diffuse angiodysplasia. Following failure of previous medical and surgical treatment, and in light of the patient's need for chronic anticoagulation due to mechanical heart valve, she was treated with somatostatin analogue, octreotide s.c. 100 μg on alternate days for 28 months. Treatment significantly decreased the occurrence of bleeding episodes, the need for hospitalization and blood transfusion requirements despite continued anticoagulant therapy. Octreotide treatment should be considered in patients with refractory gastrointestinal bleeding due to angiodysplasia in particular in those who need anticoagulant treatment.
KW - Anticoagulation therapy
KW - Diffuse angiodysplasia
KW - Somatostatin therapy
UR - http://www.scopus.com/inward/record.url?scp=0042671467&partnerID=8YFLogxK
U2 - 10.1080/00365520310001969
DO - 10.1080/00365520310001969
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C2 - 12889571
AN - SCOPUS:0042671467
SN - 0036-5521
VL - 38
SP - 801
EP - 803
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
IS - 7
ER -