@article{fce3494dfb614a9f8e928dedf582ecc3,
title = "Sodium channel localization in rat sciatic nerve following lead-induced demyelination",
abstract = "Daily intraperitoneal injections of lead acetate for several weeks were followed by a peripheral neuropathy. The conduction of impulses in the sciatic nerve became slower, but their amplitude, duration and threshold remained normal. Sodium channel labeling with specific monoclonal antibodies revealed staining at demyelinated regions, while normal axons were stained exclusively at nodes of Ranvier. These results support the view that remodelling of sodium channel distribution may contribute to impulse conduction in demyelinated fibers.",
keywords = "heavy metal intoxication, lead, monoclonal antibody, peripheral neuropathy, sciatic nerve, sodium channel",
author = "Hamutal Meiri and Sara Pri-Chen and Korczyn, \{Amos D.\}",
note = "Funding Information: We are grateful to Drs. S. Gitter, Y. Schles-singer,M . Lahav and Y. Palti for helpfuld iscussions and encouragementht roughoutth is study and to Mrs. D. Jivri for carefulp reparatioonf histological materialT. his work was supportedin part by a special granti n neurobiologfyro mThe Wolf Foundation and by the ShauOerF oundationf or Microsurgery. H.M. is a Bat-Shevad e RothschildS cholar.",
year = "1985",
month = dec,
day = "16",
doi = "10.1016/0006-8993(85)91444-1",
language = "אנגלית",
volume = "359",
pages = "326--331",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1-2",
}