Sleep Disturbances in Adolescents With Idiopathic Intracranial Hypertension

Itay Tokatly Latzer*, Riva Tauman, Noam Senderowich, Raviv Markovitz, Anat Bachar-Zipori, Ainat Klein, Hadas Meirson, Aviva Fattal-Valevski, Moran Hausman-Kedem

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: We aimed to assess the presence of sleep disturbances in adolescents with idiopathic intracranial hypertension (IIH) and to determine whether demographic, anthropometric, and clinical factors are associated with disrupted sleep. Methods: Sleep disturbances and patterns were evaluated in a cohort of adolescents (aged 12 to 18 years) with ongoing IIH and compared with a healthy age- and sex-matched control group. All participants responded to three self-rating questionnaires: the School Sleep Habits Survey (SSHS), the Pediatric Sleep Questionnaire (PSQ), and the Depression, Anxiety, and Stress Scale. The study group's demographic, clinical, laboratory, and radiological data were documented, and their association with sleep patterns was examined. Results: Thirty-three adolescents with ongoing IIH and 71 healthy controls were included. There was a significantly higher prevalence of sleep disturbances in the IIH group compared with the controls (SSHS, P < 0.001 and PSQ, P < 0.001), as well as of their independent subscales: sleep-related breathing disorders (P = 0.006), daytime sleepiness (P = 0.04), sleep/wake disruptions (P < 0.001), and sleep-related depressive tendencies (P < 0.001). According to subgroup analyses, these differences were also present between the normal-weight adolescents but not between the overweight IIH and control adolescents. No differences were found in the demographic, anthropometric, and IIH disease-related clinical measures between individuals with IIH with disrupted and normal sleep patterns. Conclusions: Sleep disturbances are common among adolescents with ongoing IIH, irrespective of their weight and disease-related characteristics. Screening adolescents with IIH for sleep disturbances is recommended as part of their multidisciplinary management.

Original languageEnglish
Pages (from-to)39-46
Number of pages8
JournalPediatric Neurology
Volume142
DOIs
StatePublished - May 2023

Keywords

  • Glymphatic
  • Headache
  • Idiopathic intracranial hypertension (IIH)
  • Obesity
  • Pseudotumor cerebri (PTC)
  • Sleep

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