Skin type, hair color, and freckles are predictors of decreased minimal erythema ultraviolet radiation dose

E. Azizi, A. Lusky, A. P. Kushelevsky, M. Schewach-Millet

Research output: Contribution to journalArticlepeer-review

Abstract

In a group of 190 white healthy subjects the skin type classification method was found valuable for differentiating subgroups with various degrees of sun sensitivity (except for 33% with borderline or unclassifiable skin type). Sun-sensitive skin types 1 and II were significantly more common among persons with light hair color or freckles, or both (p < 0.001). In each skin type category the proportion of subjects with a minimal erythema dose (MED) lower than the median MED of the entire group (%LMED) decreased significantly with increasing skin type number, and distinguished between skin types I through III better than did their mean MED values. Independent predictors of %LMED were skin type and hair color. The contribution of freckles to %LMED was skin type dependent. Age, sex, or eye color had no independent effect on %LMED. The association of skin types I and II, red or blond hair, and freckles with decreased MED may reflect genetically controlled predominance of pheomelanin (a photosensitizing molecule) in the skin of subjects with these phenotypes.

Original languageEnglish
Pages (from-to)32-38
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume19
Issue number1
DOIs
StatePublished - 1988

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