@article{8e9e15dc0df34d3a97ebc8afbff98bcf,
title = "Skin microbiome bacteria enriched following long sun exposure can reduce oxidative damage",
abstract = "Sun exposure is harmful to the skin and increases the risk of skin aging and skin cancer. Here we examined the effects of daily exposure to sun radiation on the skin microbiome in order to determine whether skim microbiome bacteria can contribute to protection from solar damage. Skin swabs were collected from ten lifeguards before and after the summer to analyse the skin microbiome. The results indicate that specific skin microbiome bacteria were enriched following the seasonal sun exposure. Especially interesting were two bacterial families - Sphingomonas and Erythrobacteraceae – which may have the ability to protect against UV radiation as they produce potentially protective compounds. We concentrated on a Sphingomonas strain and could show that it was highly resistant to UV irradiation and was able to reduce reactive oxygen species levels in human keratinocytes. These results provide a proof-of-concept for the role of the skin microbiome in protection from solar radiation.",
keywords = "Reactive oxygen species (ROS), Skin health, Skin microbiome, Sun protection, Sun radiation, UV radiation",
author = "Nurit Harel and Navit Ogen-Shtern and Leah Reshef and Dvora Biran and Ron, {Eliora Z.} and Uri Gophna",
note = "Publisher Copyright: {\textcopyright} 2023 Institut Pasteur",
year = "2023",
month = nov,
day = "1",
doi = "10.1016/j.resmic.2023.104138",
language = "אנגלית",
volume = "174",
journal = "Research in Microbiology",
issn = "0923-2508",
publisher = "Elsevier Masson s.r.l.",
number = "8",
}