Skin conductance responding in Schizophrenic patients with abnormal involuntary movements

Matti Mintz; Susana Alfisi; Mircha Sigal

doi:10.1016/0165-1781(90)90055-A

Skin conductance responding in Schizophrenic patients with abnormal involuntary movements

Matti Mintz, Susana Alfisi, Mircha Sigal

School of Psychological Sciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The present study tested the hypothesis that neuroleptic treatment modifies the skin conductance response (SCR) to loud tones. Schizophrenic patients with and without drug-induced abnormal involuntary movements were tested before and after drug withdrawal. During the on-drugs session, habituation of SCR correlated with the daily neuroleptic dose, and patients with tardive dyskinesia (TD) showed the fastest habituation of SCR. These findings were interpreted as indicating that SCR is attenuated by neuroleptics present during the examination and that TD patients demonstrate a preferential susceptibility to this effect. Withdrawal of medication resulted in slowing of SCR habituation only in TD patients, following which the entire sample showed a similar rate of habituation. These findings suggest that accelerated SCR habituation is not a stable trait of TD patients.

Original language	English
Pages (from-to)	19-27
Number of pages	9
Journal	Psychiatry Research
Volume	34
Issue number	1
DOIs	https://doi.org/10.1016/0165-1781(90)90055-A
State	Published - Oct 1990

Keywords

Parkinsonian symptoms
Schizophrenia
abnormal involuntary movements
autonomic nervous system
habituation
neuroleptics
skin conductance responding
tardive dyskinesia

Access to Document

10.1016/0165-1781(90)90055-A

Cite this

@article{1da808f5e92b4144926e44a5eabb8678,

title = "Skin conductance responding in Schizophrenic patients with abnormal involuntary movements",

abstract = "The present study tested the hypothesis that neuroleptic treatment modifies the skin conductance response (SCR) to loud tones. Schizophrenic patients with and without drug-induced abnormal involuntary movements were tested before and after drug withdrawal. During the on-drugs session, habituation of SCR correlated with the daily neuroleptic dose, and patients with tardive dyskinesia (TD) showed the fastest habituation of SCR. These findings were interpreted as indicating that SCR is attenuated by neuroleptics present during the examination and that TD patients demonstrate a preferential susceptibility to this effect. Withdrawal of medication resulted in slowing of SCR habituation only in TD patients, following which the entire sample showed a similar rate of habituation. These findings suggest that accelerated SCR habituation is not a stable trait of TD patients.",

keywords = "Parkinsonian symptoms, Schizophrenia, abnormal involuntary movements, autonomic nervous system, habituation, neuroleptics, skin conductance responding, tardive dyskinesia",

author = "Matti Mintz and Susana Alfisi and Mircha Sigal",

year = "1990",

month = oct,

doi = "10.1016/0165-1781(90)90055-A",

language = "אנגלית",

volume = "34",

pages = "19--27",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

TY - JOUR

T1 - Skin conductance responding in Schizophrenic patients with abnormal involuntary movements

AU - Mintz, Matti

AU - Alfisi, Susana

AU - Sigal, Mircha

PY - 1990/10

Y1 - 1990/10

N2 - The present study tested the hypothesis that neuroleptic treatment modifies the skin conductance response (SCR) to loud tones. Schizophrenic patients with and without drug-induced abnormal involuntary movements were tested before and after drug withdrawal. During the on-drugs session, habituation of SCR correlated with the daily neuroleptic dose, and patients with tardive dyskinesia (TD) showed the fastest habituation of SCR. These findings were interpreted as indicating that SCR is attenuated by neuroleptics present during the examination and that TD patients demonstrate a preferential susceptibility to this effect. Withdrawal of medication resulted in slowing of SCR habituation only in TD patients, following which the entire sample showed a similar rate of habituation. These findings suggest that accelerated SCR habituation is not a stable trait of TD patients.

AB - The present study tested the hypothesis that neuroleptic treatment modifies the skin conductance response (SCR) to loud tones. Schizophrenic patients with and without drug-induced abnormal involuntary movements were tested before and after drug withdrawal. During the on-drugs session, habituation of SCR correlated with the daily neuroleptic dose, and patients with tardive dyskinesia (TD) showed the fastest habituation of SCR. These findings were interpreted as indicating that SCR is attenuated by neuroleptics present during the examination and that TD patients demonstrate a preferential susceptibility to this effect. Withdrawal of medication resulted in slowing of SCR habituation only in TD patients, following which the entire sample showed a similar rate of habituation. These findings suggest that accelerated SCR habituation is not a stable trait of TD patients.

KW - Parkinsonian symptoms

KW - Schizophrenia

KW - abnormal involuntary movements

KW - autonomic nervous system

KW - habituation

KW - neuroleptics

KW - skin conductance responding

KW - tardive dyskinesia

UR - http://www.scopus.com/inward/record.url?scp=0025175526&partnerID=8YFLogxK

U2 - 10.1016/0165-1781(90)90055-A

DO - 10.1016/0165-1781(90)90055-A

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0025175526

SN - 0165-1781

VL - 34

SP - 19

EP - 27

JO - Psychiatry Research

JF - Psychiatry Research

IS - 1

ER -

Skin conductance responding in Schizophrenic patients with abnormal involuntary movements

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this