[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

I. A. Faǐn; B. I. Kuznik; A. V. Kaminskiǐ; L. Shenkman; E. M. Kustovskaia; O. G. Maksimova

[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

I. A. Faǐn^*, B. I. Kuznik, A. V. Kaminskiǐ, L. Shenkman, E. M. Kustovskaia, O. G. Maksimova

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Review article › peer-review

Abstract

We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.

Original language	English
Pages (from-to)	386-393
Number of pages	8
Journal	Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo
Volume	25
Issue number	3
State	Published - 2012

Cite this

@article{7024b34124a24185886801bb8ce2aa4d,

title = "[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].",

abstract = "We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.",

author = "Faǐn, {I. A.} and Kuznik, {B. I.} and Kaminskiǐ, {A. V.} and L. Shenkman and Kustovskaia, {E. M.} and Maksimova, {O. G.}",

year = "2012",

language = "אנגלית",

volume = "25",

pages = "386--393",

journal = "Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo",

issn = "1561-9125",

publisher = "Eskulap",

number = "3",

}

[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people]. / Faǐn, I. A.; Kuznik, B. I.; Kaminskiǐ, A. V. et al.

In: Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo, Vol. 25, No. 3, 2012, p. 386-393.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - [SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

AU - Faǐn, I. A.

AU - Kuznik, B. I.

AU - Kaminskiǐ, A. V.

AU - Shenkman, L.

AU - Kustovskaia, E. M.

AU - Maksimova, O. G.

PY - 2012

Y1 - 2012

N2 - We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.

AB - We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.

UR - http://www.scopus.com/inward/record.url?scp=84872533022&partnerID=8YFLogxK

M3 - סקירה

AN - SCOPUS:84872533022

VL - 25

SP - 386

EP - 393

JO - Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo

JF - Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo

SN - 1561-9125

IS - 3

ER -

[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

Abstract

Other files and links

Fingerprint

Cite this