[SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

I. A. Faǐn, B. I. Kuznik, A. V. Kaminskiǐ, L. Shenkman, E. M. Kustovskaia, O. G. Maksimova

Research output: Contribution to journalReview articlepeer-review

Abstract

We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.

Original languageEnglish
Pages (from-to)386-393
Number of pages8
JournalAdvances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo
Volume25
Issue number3
StatePublished - 2012

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