TY - JOUR
T1 - [SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].
AU - Faǐn, I. A.
AU - Kuznik, B. I.
AU - Kaminskiǐ, A. V.
AU - Shenkman, L.
AU - Kustovskaia, E. M.
AU - Maksimova, O. G.
PY - 2012
Y1 - 2012
N2 - We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.
AB - We have conducted a study on a large group of healthy and sick subjects and have demonstrated that a new index of coagulativety (SKF), based on measurement of the laser speckle signal from the finger root, correlates with chronological age ranging from 1 to 85 years old. The kinds of non-invasive measurements were obtained during two measurement sessions: one with the application of over-systolic occlusion and another without application of the occlusion. The very significant correlation with age was noted both during the stasis stage and during the non-occluding stage. We observed a higher SKF index in sick subjects, correlating directly with severity of illness. We speculated that the observed phenomena are caused by temporarily fluctuations in local blood viscosity associated with interactions of the Red Blood Cells and endothelial cells.
UR - http://www.scopus.com/inward/record.url?scp=84872533022&partnerID=8YFLogxK
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AN - SCOPUS:84872533022
VL - 25
SP - 386
EP - 393
JO - Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo
JF - Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo
SN - 1561-9125
IS - 3
ER -