TY - JOUR
T1 - Six Weeks of Intensive Treadmill Training Improves Gait and Quality of Life in Patients With Parkinson's Disease
T2 - A Pilot Study
AU - Herman, Talia
AU - Giladi, Nir
AU - Gruendlinger, Leor
AU - Hausdorff, Jeffrey M.
PY - 2007/9
Y1 - 2007/9
N2 - Herman T, Giladi N, Gruendlinger L, Hausdorff JM. Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: a pilot study. Objective: To evaluate the effects of 6 weeks of intensive treadmill training on gait rhythmicity, functional mobility, and quality of life (QOL) in patients with Parkinson's disease (PD). Design: An open-label, before-after pilot study. Setting: Outpatient movement disorders clinic. Participants: Nine patients with PD who were able to ambulate independently and were not demented. Mean age was 70±6.8 years. Patients had mild to moderate PD (Hoehn and Yahr stage range, 1.5-3). Interventions: Patients walked on a treadmill for 30 minutes during each training session, 4 training sessions a week, for 6 weeks. Once a week, usual overground walking speed was re-evaluated and the treadmill speed was adjusted accordingly. Main Outcome Measures: The 39-item Parkinson's Disease Questionnaire (PDQ-39), motor part of the Unified Parkinson's Disease Rating Scale (UPDRS), gait speed, stride time variability, swing time variability, and the Short Physical Performance Battery (SPPB). Results: A comparison of the measures taken before and after the treadmill intervention indicates general improvement. QOL, as measured by the PDQ-39, was reduced (improved) from 32 to 22 (P<.014). Parkinsonian symptoms, as measured by the UPDRS, decreased (improved) from 29 to 22 (P<.043). Usual gait speed increased from 1.11 to 1.26m/s (P<.014). Swing time variability was lower (better) in all but one patient, changing from 3.0% to 2.3% (P<.06). Scores on the SPPB also improved (P<.008). Interestingly, many of the improvements persisted even 4 weeks later. Conclusions: These results show the potential to enhance gait rhythmicity in patients with PD and suggest that a progressive and intensive treadmill training program can be used to minimize impairments in gait, reduce fall risk, and increase QOL in these patients.
AB - Herman T, Giladi N, Gruendlinger L, Hausdorff JM. Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: a pilot study. Objective: To evaluate the effects of 6 weeks of intensive treadmill training on gait rhythmicity, functional mobility, and quality of life (QOL) in patients with Parkinson's disease (PD). Design: An open-label, before-after pilot study. Setting: Outpatient movement disorders clinic. Participants: Nine patients with PD who were able to ambulate independently and were not demented. Mean age was 70±6.8 years. Patients had mild to moderate PD (Hoehn and Yahr stage range, 1.5-3). Interventions: Patients walked on a treadmill for 30 minutes during each training session, 4 training sessions a week, for 6 weeks. Once a week, usual overground walking speed was re-evaluated and the treadmill speed was adjusted accordingly. Main Outcome Measures: The 39-item Parkinson's Disease Questionnaire (PDQ-39), motor part of the Unified Parkinson's Disease Rating Scale (UPDRS), gait speed, stride time variability, swing time variability, and the Short Physical Performance Battery (SPPB). Results: A comparison of the measures taken before and after the treadmill intervention indicates general improvement. QOL, as measured by the PDQ-39, was reduced (improved) from 32 to 22 (P<.014). Parkinsonian symptoms, as measured by the UPDRS, decreased (improved) from 29 to 22 (P<.043). Usual gait speed increased from 1.11 to 1.26m/s (P<.014). Swing time variability was lower (better) in all but one patient, changing from 3.0% to 2.3% (P<.06). Scores on the SPPB also improved (P<.008). Interestingly, many of the improvements persisted even 4 weeks later. Conclusions: These results show the potential to enhance gait rhythmicity in patients with PD and suggest that a progressive and intensive treadmill training program can be used to minimize impairments in gait, reduce fall risk, and increase QOL in these patients.
KW - Cues
KW - Gait
KW - Parkinson's disease
KW - Quality of life
KW - Rehabilitation
KW - Treadmill test
UR - http://www.scopus.com/inward/record.url?scp=34548420215&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2007.05.015
DO - 10.1016/j.apmr.2007.05.015
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C2 - 17826461
AN - SCOPUS:34548420215
SN - 0003-9993
VL - 88
SP - 1154
EP - 1158
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 9
ER -