Single stranded DNA translocation through a fluctuating nanopore

O. Flomenbom, J. Klafter

Research output: Contribution to journalConference articlepeer-review


We investigate the translocation of a single stranded DNA (ssDNA) through a pore, which fluctuates between two conformations, by using coupled master equations (ME). The probability density function (PDF) of the first passage times (FPT) of the translocation process is calculated, displaying a triple, double or mono-peaked behavior, depending on the system parameters. An analytical expression for the mean first passage time (MFPT) of the translocation process is derived, and provides an extensive characterization of the translocation process.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalMaterials Research Society Symposium - Proceedings
StatePublished - 2003
EventDynamics in Small Confining Systems - 2003 - Boston, MA, United States
Duration: 1 Dec 20034 Dec 2003


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