TY - JOUR
T1 - Single-scan 2D NMR correlations by multiple coherence transfers
AU - Gal, Maayan
AU - Frydman, Lucio
N1 - Funding Information:
This research was supported by the Israel Science Foundation (ISF 447/09), the European Commission (EU-NMR contract No. 026145), by a Helen and Martin Kimmel Award for Innovative Investigation and by the generosity of the Perlman Family Foundation.
PY - 2010/4
Y1 - 2010/4
N2 - A new scheme for the acquisition of heteronuclear 2D correlations in NMR spectroscopy within a single scan, is proposed and demonstrated. The principles of this new scheme resemble those of Mansfield's "k-space walk" proposal, in the sense that they rely on repetitively transferring spin coherences back-and-forth between the two spin systems to be correlated. It is shown that if properly executed, these transfers enable the equivalent of a continuous sampling of the time-domain space supporting a 2D heteronuclear single-quantum correlation NMR spectrum. Details on how to execute the resulting "time-domain walk" experiments are given, and examples comparing it against conventional and other single-scan 2D acquisition alternatives are shown. Advantages, opportunities, and main drawbacks of this new ultrafast approach to 2D NMR, are briefly discussed.
AB - A new scheme for the acquisition of heteronuclear 2D correlations in NMR spectroscopy within a single scan, is proposed and demonstrated. The principles of this new scheme resemble those of Mansfield's "k-space walk" proposal, in the sense that they rely on repetitively transferring spin coherences back-and-forth between the two spin systems to be correlated. It is shown that if properly executed, these transfers enable the equivalent of a continuous sampling of the time-domain space supporting a 2D heteronuclear single-quantum correlation NMR spectrum. Details on how to execute the resulting "time-domain walk" experiments are given, and examples comparing it against conventional and other single-scan 2D acquisition alternatives are shown. Advantages, opportunities, and main drawbacks of this new ultrafast approach to 2D NMR, are briefly discussed.
KW - Coherence transfer processes
KW - HSQC
KW - Multidimensional spectroscopy
KW - Ultrafast 2D NMR
UR - http://www.scopus.com/inward/record.url?scp=77949489122&partnerID=8YFLogxK
U2 - 10.1016/j.jmr.2009.10.013
DO - 10.1016/j.jmr.2009.10.013
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AN - SCOPUS:77949489122
SN - 1090-7807
VL - 203
SP - 311
EP - 315
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
IS - 2
ER -