Abstract
A single 5-gm dose of mezlocillin or a placebo was administered intravenously 30 minutes before surgery to patients undergoing emergency cesarean section. The assignment of drug or placebo was randomized. Postoperative morbidity occurred in 62.5% of patients receiving placebo and in 18.4% of those receiving mezlocillin (P < 0.001). The incidences of febrile morbidity, endometritis, and urinary tract infection were significantly lower in the group given mezlocillin. Other benefits of antibiotic prophylaxis included a shorter hospital stay and no serious infections in the group given mezlocillin.
| Original language | English |
|---|---|
| Pages (from-to) | 507-511 |
| Number of pages | 5 |
| Journal | Clinical Therapeutics |
| Volume | 7 |
| Issue number | 4 |
| State | Published - 1985 |
| Externally published | Yes |