Simultaneous measurement of the photoplethysmographic signal variability in the right and left hands

M. Nitzan*, J. J. Vatine, A. Babchenko, B. Khanokh, J. Tsenter, J. Stessman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The photoplethysmographic (PPG) signal, which is a measure of the systolic oscillations in the tissue blood volume, spontaneously fluctuates in the respiration rate and in lower frequencies similar to the heart rate fluctuations. In the current study, the low frequency fluctuations, which are attributed to the sympathetic nervous system activity, were obtained from PPG examinations simultaneously performed on the right and the left hands of healthy subjects and hemiplegic patients. For normal subjects, the fluctuations in the two hands were found to be correlated, demonstrating their central origin. For some of the hemiplegic patients, the coefficient of correlation between the right and the left hands was significantly lower than the normal range. The simultaneous measurement of the PPG signal fluctuations in both hands provides information on the adequate function of the autonomic nervous system.

Original languageEnglish
Pages (from-to)189-195
Number of pages7
JournalLasers in Medical Science
Issue number3
StatePublished - 1998
Externally publishedYes


FundersFunder number
Israeli Ministry of Science
Ministry of Aliyah and Immigrant Absorption


    • Autonomic nervous system
    • Hemiplegic patients
    • Photoplethysmography
    • Tissue blood volume variability


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