Silicon micro-needles with flexible interconnections

G. Holman, Y. Hanein, R. C. Wyeth, A. O.D. Willows, D. D. Denton, K. F. Böhringer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

A flexible polyimide-based interconnect scheme was developed to realize isolated needle-like microelectrodes. A simple fabrication approach allows the integration of micromachined silicon needles with a larger silicon base designed to carry elements such as amplifiers, battery or memory. The interconnecting scheme uses two polyimide layers to sandwich a metallic layer. The metal layer forms the electrical connection between the silicon base and the micro-electrodes, while the polyimide layers provide flexible insulation. The current design allows convenient handling of the device during implantation and minimal mechanical load on the implanted region. The device can conform to the surface of neural tissue and allows convenient interfacing with rugged and dynamic tissues. Prototype devices were tested for usability and animal-compatibility. The devices were implanted in sea slugs (Tritonia diomedea) and extracellular signals were acquired. Tritonia diomedea show full recovery from surgery and implantation, and survive up to a minimum of fourteen days with the ability to perform normal behaviors.

Original languageEnglish
Title of host publication2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings
EditorsDavid Beebe, Andre Dittmar
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages255-260
Number of pages6
ISBN (Electronic)0780374800, 9780780374805
DOIs
StatePublished - 2002
Externally publishedYes
Event2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Madison, United States
Duration: 2 May 20024 May 2002

Publication series

Name2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

Conference

Conference2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology
Country/TerritoryUnited States
CityMadison
Period2/05/024/05/02

Funding

FundersFunder number
DARPA Bio
Microsoft Research and Tanner Research Inc.
NSF CISE Postdoctoral Research Associates EIA-0072744
National Sciences and Research Council
National Science FoundationEIA-0072744
David and Lucile Packard Foundation2000-0 1763
Defense Advanced Research Projects AgencyMD A972-01-1-002
Intel Corporation
Agilent Technologies
Microsoft Research

    Keywords

    • Intracellular
    • flexible
    • micro-electrodes
    • needles

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