Sialyltransferase activity in plasma cells of multiple myeloma

A. M. Cohen*, D. Allalouf, M. Djaldetti, K. Weigl, N. Lehrer, H. Levinsky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A marked elevation of sialyltransferase activity (STA) was observed in a solid tumor of plasma cells, which had been removed from a patient with multiple myeloma (MM), as compared to normal lymphatic tissues. STA was also determined in mononuclear bone marrow cells of 10 patients with MM and found to be 12 times higher than that of bone marrow mononuclear cells from 5 patients with non‐malignant disorders (with less than 1% plasma cells in the bone marrow aspirate). A significant correlation was found between STA and the number of plasma cells in the bone marrow aspirate.

Original languageEnglish
Pages (from-to)191-194
Number of pages4
JournalEuropean Journal of Haematology
Volume43
Issue number3
DOIs
StatePublished - Sep 1989

Keywords

  • myeloma
  • plasma cell dyscrasia
  • sialyltransferase

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