Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes

Rebecca K. West; Ramit Ravona-Springer; Anthony Heymann; James Schmeidler; Derek Leroith; Keren Koifman; Elizabeth Guerrero-Berroa; Rachel Preiss; Hadas Hoffman; Jeremy M. Silverman; Michal Schnaider Beeri

doi:10.3233/JAD-142049

Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes

Rebecca K. West^*, Ramit Ravona-Springer, Anthony Heymann, James Schmeidler, Derek Leroith, Keren Koifman, Elizabeth Guerrero-Berroa, Rachel Preiss, Hadas Hoffman, Jeremy M. Silverman, Michal Schnaider Beeri

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.

Original language	English
Pages (from-to)	927-935
Number of pages	9
Journal	Journal of Alzheimer's Disease
Volume	44
Issue number	3
DOIs	https://doi.org/10.3233/JAD-142049
State	Published - 2015
Externally published	Yes

Keywords

Cognitive performance
height
risk factors
type 2 diabetes mellitus
vascular dementia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3233/JAD-142049

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title = "Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes",

abstract = "We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.",

keywords = "Cognitive performance, height, risk factors, type 2 diabetes mellitus, vascular dementia",

author = "West, {Rebecca K.} and Ramit Ravona-Springer and Anthony Heymann and James Schmeidler and Derek Leroith and Keren Koifman and Elizabeth Guerrero-Berroa and Rachel Preiss and Hadas Hoffman and Silverman, {Jeremy M.} and Beeri, {Michal Schnaider}",

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doi = "10.3233/JAD-142049",

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AU - West, Rebecca K.

AU - Ravona-Springer, Ramit

AU - Heymann, Anthony

AU - Schmeidler, James

AU - Leroith, Derek

AU - Koifman, Keren

AU - Guerrero-Berroa, Elizabeth

AU - Preiss, Rachel

AU - Hoffman, Hadas

AU - Silverman, Jeremy M.

AU - Beeri, Michal Schnaider

PY - 2015

Y1 - 2015

N2 - We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.

AB - We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.

KW - Cognitive performance

KW - height

KW - risk factors

KW - type 2 diabetes mellitus

KW - vascular dementia

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ER -

Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes

Abstract

Keywords

UN SDGs

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