Shear stress related blood damage along the cusp of a tri-leaflet prosthetic valve

S. Einav, H. Reul, G. Rau, D. Elad

Research output: Contribution to journalArticlepeer-review

Abstract

Blood flowing through a prosthetic heart valve can be damaged by flow induced shear forces. Fluid dynamics variables and geometric factors play an important role in the evaluation of shear-stress-related blood damage. Central-flow prosthetic valves have been considered as an optimal replacement for mechanical and biological valves. Recently it was shown that shear stress distribution along the surface of a polyurethane cusp reaches values that can damage the blood elements. A mathematical model correlating the effects of shear stresses on blood corpuscles with clinical findings was employed in vitro. The model can be applied to the effects of blood-surface interaction and is of clinical relevance.

Original languageEnglish
Pages (from-to)716-720
Number of pages5
JournalInternational Journal of Artificial Organs
Volume14
Issue number11
DOIs
StatePublished - 1991

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