Severe postpartum pulmonary, cardiac, and renal syndrome associated with antiphospholipid antibodies

Michael J. Kupferminc, Men Jean Lee, David Green, Alan M. Peaceman

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The antiphospholipid antibody syndrome has been associated with thromboembolic events, thrombocytopenia, fetal death, fetal growth retardation, and early-onset severe preeclampsia. Case: A postpartum woman developed fever, pulmonary infiltrates, cardiac conduction defects, and renal insufficiency following severe preeclampsia. She tested positive for lupus anticoagulant and anticardiolipin antibody, and responded to steroid therapy and plasmapheresis. Conclusion: The postpartum multi-system involvement suggests that a variety of clinical presentations may be associated with antiphospholipid antibodies. Treatment with plasmapheresis or corticosteroids may be of value in similar cases.

Original languageEnglish
Pages (from-to)806-807
Number of pages2
JournalObstetrics and Gynecology
Volume83
Issue number5
StatePublished - May 1994
Externally publishedYes

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