TY - JOUR
T1 - Serum xanthine oxidase in jaundice
AU - Giler, S. H.
AU - Sperling, O.
AU - Brosh, S.
AU - Urca, I.
AU - de Vries, A.
PY - 1975/8/18
Y1 - 1975/8/18
N2 - Serum xanthine oxidase activity was measured by a radiochemical method in 137 consecutive patients with jaundice of varying etiology and in 40 non-jaundiced patients with liver or other disease. Serum xanthine oxidase was markedly increased, up to 50 times the upper normal limit (mean + 2 S.D.), in 32 out of 34 patients with infectious hepatitis. A slight elevation of serum xanthine oxidase, up to twice the upper normal limit, was found in 2 out of 49 patients with extrahepatic obstructive jaundice and in 4 out of 20 patients with chronic renal failure. In comparison to serum glutamic-oxaloacetic transaminase and lactate dehydrogenase serum xanthine oxidase appeared to be the more sensitive and specific indicator of acute hepatocellular damage.
AB - Serum xanthine oxidase activity was measured by a radiochemical method in 137 consecutive patients with jaundice of varying etiology and in 40 non-jaundiced patients with liver or other disease. Serum xanthine oxidase was markedly increased, up to 50 times the upper normal limit (mean + 2 S.D.), in 32 out of 34 patients with infectious hepatitis. A slight elevation of serum xanthine oxidase, up to twice the upper normal limit, was found in 2 out of 49 patients with extrahepatic obstructive jaundice and in 4 out of 20 patients with chronic renal failure. In comparison to serum glutamic-oxaloacetic transaminase and lactate dehydrogenase serum xanthine oxidase appeared to be the more sensitive and specific indicator of acute hepatocellular damage.
UR - http://www.scopus.com/inward/record.url?scp=0016704612&partnerID=8YFLogxK
U2 - 10.1016/0009-8981(75)90375-7
DO - 10.1016/0009-8981(75)90375-7
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AN - SCOPUS:0016704612
SN - 0009-8981
VL - 63
SP - 37
EP - 40
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 1
ER -
