Serum-specific antibodies for chlamydia trachomatis in preterm premature rupture of the membranes

Ilan Cohen, Ella Tenenbaum, Moshe Fejgin, Galia Michaeli, Yoram Beyth, Israel Sarov

Research output: Contribution to journalArticlepeer-review

Abstract

A case control study was performed to examine possible morbidity associated with Chlamydia trachomatis in 15 pregnant women with idiopathic preterm premature rupture of the membranes (PROM; group A), and in two control groups, 35 healthy preterm pregnant women (group B), and 43 healthy pregnant women at term (group C). Serum C. trachomatis IgG and IgA specific antibodies were determined using the single serovar (L2) inclusion immunoperoxidase assay. There were no significant differences in the prevalence rate of elevated levels of chlamydia IgG specific antibodies (titer ≥: 1:128) between pregnant women suffering from idiopathic preterm PROM, as compared to healthy preterm and term pregnant women (20, 28 and 26%, respectively). Nor were there any significant differences in the prevalence rate of elevated levels of chlamydia IgA specific antibodies (titer ≥: 1:16) between pregnant women with idiopathic preterm PROM, as compared to healthy preterm and term pregnant women (20, 20 and 17%, respectively). These findings do not support the assumption that C. trachomatis may play role in preterm PROM.

Original languageEnglish
Pages (from-to)155-158
Number of pages4
JournalGynecologic and Obstetric Investigation
Volume30
Issue number3
DOIs
StatePublished - 1990
Externally publishedYes

Keywords

  • Antibodies
  • Chlamydia trachomatis
  • Membranes
  • Preterm and premature rupture of

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