Serum and effluent lysozyme (muramidase) activity in CAPD patients.

A. Kagan, Y. Bar-Khayim, A. Yaari, M. Fainaru, P. Resnitzky

Research output: Contribution to journalArticlepeer-review

Abstract

The elevated serum lysozyme activity in 13 chronic renal failure patients (n = 26) dropped significantly during their first three months of CAPD and subsequently returned to initial levels. When compared with peritoneal mass transfer of lysozyme and serum creatinine levels, a distinct correlation was observed between these and the fluctuations in serum lysozyme activity recorded up to three years of CAPD (r = 0.319, P less than 0.05 and r = 0.425, P less than 0.025, respectively). A notable drop in the mass transfer of this low molecular weight protein took place after the first hour of dialysis. We concluded that long-term CAPD does not affect serum lysozyme activity and that passive loss across the peritoneal membrane could account for the lysozyme found in the effluent fluid.

Original languageEnglish
Pages (from-to)154-156
Number of pages3
JournalAdvances in peritoneal dialysis. Conference on Peritoneal Dialysis
Volume5
StatePublished - 1989
Externally publishedYes

Fingerprint

Dive into the research topics of 'Serum and effluent lysozyme (muramidase) activity in CAPD patients.'. Together they form a unique fingerprint.

Cite this