Serum alpha fetal protein in a three year old child with hepatoma

Y. Shoenfeld, A. I. Pick, S. Schreibman, H. Kessler, M. Dintzman

Research output: Contribution to journalArticlepeer-review

Abstract

A 3 yr old child with primary hepatocellular carcinoma and high AFP concentrations is described. Following hemihepatectomy, a sharp decrease and return to normal of serum AFP concentrations indicated the completeness of the surgical procedure. Repeat normal serum AFP concentrations (less than 19 ng/ml), found during a 3 year followup, correlated well with the absence of clinical, laboratory and x ray evidence of tumor recurrence. The differential diagnosis of abnormal AFP concentrations in childhood is discussed, and the importance of the AFP assay in the followup of posthemihepatectomy patients for the assessment of the completeness of the surgical procedure, the prognosis, and the early detection of tumor recurrence is stressed.

Original languageEnglish
Pages (from-to)407-414
Number of pages8
JournalUnknown Journal
Volume62
Issue number4
DOIs
StatePublished - 1976

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