Serotonin (5‐HT) uptake by blood platelets in anorexia nervosa

Z. Zemishlany, I. Modai, A. Apter, Z. Jerushalmy, E. Samuel, S. Tyano

Research output: Contribution to journalArticlepeer-review


ABSTRACT— Platelet serotonin (5‐HT) uptake was determined in 15 underweight anorexia nervosa patients and a control group of 15 healthy individuals. The Vmax (picomoles/108 platelets/5 min) was 424 ± 103 in patients and 424 ± 69 in controls. The Km was 1.19 ± 0.2 μM in patients and 1.08 ± 0.17 μM in controls. The differences between the groups were not significant. These findings do not support the hypothesis that serotonin metabolism is disturbed in anorexia nervosa.

Original languageEnglish
Pages (from-to)127-130
Number of pages4
JournalActa Psychiatrica Scandinavica
Issue number2
StatePublished - Feb 1987


  • affective disorder
  • anorexia nervosa
  • serotonin


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