Abstract
Accurate serological assays are desirable for the diagnosis of inflammatory bowel disease. Among several serological markers anti-Saccharomyces cerevisiae mannan antibodies and perinuclear antineutrophil cytoplasmic autoantibodies are highly disease specific for Crohn's disease and ulcerative colitis, respectively. Combining the two improves their specificity. Sensitivity, however, is still low. Due to lack of standardization and vast interobserver variability, they cannot be used as the only diagnostic criteria but can assist clinicians in diagnosing and categorizing patients with inflammatory bowel disease as well as in helping them to take therapeutic decisions.
| Original language | English |
|---|---|
| Pages (from-to) | 103-105 |
| Number of pages | 3 |
| Journal | European Journal of Gastroenterology and Hepatology |
| Volume | 14 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2002 |
| Externally published | Yes |
Keywords
- Anti-Saccharomyces cerevisiae mannan antibodies
- Crohn's disease
- Inflammatory bowel disease
- Perinuclear antineutrophil cytoplasmic autoantibodies
- Ulcerative colitis