TY - JOUR
T1 - Serologic markers in inflammatory bowel disease
T2 - tools for better diagnosis and disease stratification.
AU - Dotan, Iris
PY - 2007/12
Y1 - 2007/12
N2 - In the last decade, new serologic markers have been identified, and attempts to delineate their potential roles in inflammatory bowel disease diagnosis, determination of prognosis and identification of apparently healthy subjects at risk have significantly increased our knowledge. In this review, the major serologic markers will be described, focusing on their common features as a group. It is predicted that within the next 5 years, panels of antibodies will prove to have a significant impact on disease diagnosis and stratification, as well as on the identification of populations at risk and the prediction of response to treatment. Thus, it is expected that they will become useful clinical tools that will enable an improved, 'tailored' approach to inflammatory bowel disease patients.
AB - In the last decade, new serologic markers have been identified, and attempts to delineate their potential roles in inflammatory bowel disease diagnosis, determination of prognosis and identification of apparently healthy subjects at risk have significantly increased our knowledge. In this review, the major serologic markers will be described, focusing on their common features as a group. It is predicted that within the next 5 years, panels of antibodies will prove to have a significant impact on disease diagnosis and stratification, as well as on the identification of populations at risk and the prediction of response to treatment. Thus, it is expected that they will become useful clinical tools that will enable an improved, 'tailored' approach to inflammatory bowel disease patients.
UR - http://www.scopus.com/inward/record.url?scp=61549109924&partnerID=8YFLogxK
U2 - 10.1586/17474124.1.2.265
DO - 10.1586/17474124.1.2.265
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C2 - 19072419
AN - SCOPUS:61549109924
SN - 1747-4124
VL - 1
SP - 265
EP - 274
JO - Expert Review of Gastroenterology and Hepatology
JF - Expert Review of Gastroenterology and Hepatology
IS - 2
ER -