Seroepidemiology of hepatitis b and d virus infection among intravenous drug addicts in israel

Michael Dan, Meir Rock, Pearl Lilos, Shulamit Bar Shany

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate the prevalence of hepatitis B virus (HBV) and hepatitis D virus (HDV) infection among intravenous drug addicts (IVDA) in Israel, serum samples were collected from 400 asymptomatic individuals attending a methadone clinic in Tel Aviv. Overall 5.5% were HBsAg positive, 2.4% HBeAg positive, 52% anti-HBc positive and 6.6% were positive for anti-HD. Anti-HD was identified in 18% of addicts who were HBsAg positive and in 3% who were HBsAg negative and anti-HBc positive. Strong correlation was found between positivity to HBV antibodies and age and duration of drug use. History of jaundice correlated more strongly with anti-HD positivity than with presence of antibodies to HBV. We conclude that Israeli IVDA are less exposed to HBV and HDV infection than their North American and European counterparts.

Original languageEnglish
Pages (from-to)140-143
Number of pages4
JournalInternational Journal of Epidemiology
Volume22
Issue number1
DOIs
StatePublished - Feb 1993
Externally publishedYes

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