Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation

Joseph Kapelushnik; Dan Engelhard; Jayesh Mehta; Reuven Or; Yuval Brandstetter; Elie Picard; Gabriel Cividalli; Arnon Nagler

doi:10.1002/jmv.1890460216

Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation

Joseph Kapelushnik^*
, Dan Engelhard
, Jayesh Mehta
, Reuven Or
, Yuval Brandstetter
, Elie Picard
, Gabriel Cividalli
, Arnon Nagler

^*Corresponding author for this work

Hadassah University Medical Centre

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 6‐month‐old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV‐ and CMV‐induced lung injury in these life‐threatening infections. © 1995 Wiley‐Liss, Inc.

Original language	English
Pages (from-to)	169-171
Number of pages	3
Journal	Journal of Medical Virology
Volume	46
Issue number	2
DOIs	https://doi.org/10.1002/jmv.1890460216
State	Published - Jun 1995
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

bone marrow transplantation
cytomegalovirus
familial hemophagocytic lymphohistiocytosis
interstitial pneumonia
respiratory syncytial virus

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10.1002/jmv.1890460216

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title = "Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation",

abstract = "A 6‐month‐old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV‐ and CMV‐induced lung injury in these life‐threatening infections. {\textcopyright} 1995 Wiley‐Liss, Inc.",

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year = "1995",

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doi = "10.1002/jmv.1890460216",

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AU - Kapelushnik, Joseph

AU - Engelhard, Dan

AU - Mehta, Jayesh

AU - Or, Reuven

AU - Brandstetter, Yuval

AU - Picard, Elie

AU - Cividalli, Gabriel

AU - Nagler, Arnon

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AB - A 6‐month‐old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV‐ and CMV‐induced lung injury in these life‐threatening infections. © 1995 Wiley‐Liss, Inc.

KW - bone marrow transplantation

KW - cytomegalovirus

KW - familial hemophagocytic lymphohistiocytosis

KW - interstitial pneumonia

KW - respiratory syncytial virus

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ER -

Sequential respiratory syncytial virus cytomegalovirus pneumonia following bone marrow transplantation

Abstract

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Keywords

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