Sequential regional phase mapping of radionuclide gated biventriculograms in patients with sustained ventricular tachycardia: Close correlation with electrophysiologic characteristics

Steven Swiryn, Dan Pavel, Ernest Byrom, Robert A. Bauernfeind, Boris Strasberg, Edwin Palileo, Wiltred Lam, Christopher R.C. Wyndham, Kenneth M. Rosen

Research output: Contribution to journalArticlepeer-review

Abstract

Radionuclide (RNA) gated studies were performed during sinus rhythm and during spontaneous or induced sustained ventricular tachycardia (VT) in six patients with clinical VT. Fourier analysis of time-activity variation was used to calculate a RNA phase value for each pixel in the image. Color coding of each pixel according to its calculated phase resulted in a RNA phase map of the ventricles. The following results were considered to be consistent with the known electrophysiology of VT: (1) the phase map correlated with QRS morphology and axis in most but not all tachycardias; (2) earliest phase usually demonstrated the VT origin to be at the border of the ventricular wall motion abnormality; (3) endocardial mapping (available in one patient) showed close correlation with RNA phase mapping; (4) in three patients with ischemic heart disease, VT with left bundle branch block (LBBB) pattern had earliest LV phase along the septum; and (S) tornone patient imaged during two different VT morphologies, the tachycardias had earliest phase at different borders of the same wall motion abnormality with differing progression of phase across the ventricles. RNA phase mapping of VT is feasible and appears to provide data consistent with the electrophysiology of this arrhythmia.

Original languageEnglish
Pages (from-to)319-332
Number of pages14
JournalAmerican Heart Journal
Volume103
Issue number3
DOIs
StatePublished - Mar 1982
Externally publishedYes

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