Separation of complement‐dependent and lymphocytedependent cytotoxic activity in human sera

June L. Miller, D. L. Mann, I. Yust

Research output: Contribution to journalArticlepeer-review

Abstract

Two human sera having both complement‐dependent and lymphocyte‐dependent antibody activities (CDA, LDA) were applied to isoelectrofocusing columns. Maximum LDA activity for both sera was found focused at a higher pH than maximum CDA activity. The studies suggest that LDA molecules may exist without having complement‐dependent activity.

Original languageEnglish
Pages (from-to)546-548
Number of pages3
JournalEuropean Journal of Immunology
Volume5
Issue number8
DOIs
StatePublished - Aug 1975

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