Separation and imaging of circulating tumor cells using hybrid graphene oxide based nanotechnology

Sudarson Sekhar Sinha, Aruna Vangara, Avijit Pramanik, Suhash Reddy Chavva, Yongliang Shi, Stacy Jones, Jasmine Burrell, Craig Hawker, Paresh C. Ray

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Circulating tumor cells (CTCs) are the “seed and soil” for cancer metastases development, which is responsible for >90% of cancer-related deaths. Current chapter review the recent development of hybrid graphene oxide based nanotechnology, mainly from authors own contributions, which can be used for selective detection and separation of different types of CTCs from infected blood. CTCs separation has been performed using magnetic field and CTCs mapping has been performed using two photon and single photon fluorescence spectroscopy.

Original languageEnglish
Title of host publicationCirculating Tumor Cells (CTCs)
Subtitle of host publicationDetection Methods, Health Impact and Emerging Clinical Challenges
PublisherNova Science Publishers, Inc.
Pages19-45
Number of pages27
ISBN (Electronic)9781634845274
ISBN (Print)9781634844970
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • 2D and 3D graphene oxide membrane
  • CTCs indentifications
  • Hybrid graphene oxide
  • Magnetic separation of CTCs
  • Two-photon imaging of CTCs

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