Self-immolative dendrimers

Roey J. Amir*, Neta Pessah, Marina Shamis, Doron Shabat

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

276 Scopus citations


Docking the tails: The triggering of a single cleavage at the core of a new class of dendrimers (see, for example, the second generation dendron) results in a spontaneous chain fragmentation and the release all of the tail (reporter) units. Such dendrimers may be applied as a general platform for prodrugs or sensor molecules for enzymatic activity.

Original languageEnglish
Pages (from-to)4494-4499
Number of pages6
JournalAngewandte Chemie - International Edition
Issue number37
StatePublished - 29 Sep 2003


  • Amides
  • Dendrimers
  • Dyes
  • Fragmentation
  • Rearrangement


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