Self-assembly of cyclic dipeptides: Platforms for functional materials

Yu Chen, Kai Tao, Wei Ji, Pandeeswar Makam, Sigal Rencus-Lazar, Ehud Gazit*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Supramolecular self-assembled functional materials comprised of cyclic dipeptide building blocks have excellent prospects for biotechnology applications due to their exceptional structural rigidity, morphological flexibility, ease of preparation and modification. Although the pharmacological uses of many natural cyclic dipeptides have been studied in detail, relatively little is reported on the engineering of these supramolecular architectures for the fabrication of functional materials. In this review, we discuss the progress in the design, synthesis, and characterization of cyclic dipeptide supramolecular nanomaterials over the past few decades, highlighting applications in biotechnology and optoelectronics engineering.

Original languageEnglish
Pages (from-to)688-697
Number of pages10
JournalProtein and Peptide Letters
Issue number8
StatePublished - 2020


FundersFunder number
Huawei Technologies Co., Ltd.
Horizon 2020 Framework Programme
European Research Council
Huawei Technologies
Center for Nanoscience and Nanotechnology, Tel Aviv University
Horizon 2020694426


    • Biomaterial
    • Bionanotechnology
    • Cyclic dipeptide
    • Optoelectronic
    • Photoluminescence
    • Self-assembly


    Dive into the research topics of 'Self-assembly of cyclic dipeptides: Platforms for functional materials'. Together they form a unique fingerprint.

    Cite this