Self-assembly of a tetrahedral lectin into predesigned diamondlike protein crystals

Nir Dotan; Dorit Arad; Felix Frolow; Amihay Freeman

doi:10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D

Self-assembly of a tetrahedral lectin into predesigned diamondlike protein crystals

Nir Dotan, Dorit Arad, Felix Frolow, Amihay Freeman

Biotechnology

Research output: Contribution to journal › Article › peer-review

Abstract

Binding sites analogous to those of sp³ carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C₂ spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.

Original language	English
Pages (from-to)	2363-2366
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	38
Issue number	16
DOIs	https://doi.org/10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D
State	Published - 12 Aug 1999

Keywords

Crystal engineering
Lectins
Molecular modeling
Proteins
Supramolecular chemistry

Access to Document

10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D

Cite this

@article{527abc94a81e4449b8f84f707fca80a0,

title = "Self-assembly of a tetrahedral lectin into predesigned diamondlike protein crystals",

abstract = "Binding sites analogous to those of sp3 carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C2 spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.",

keywords = "Crystal engineering, Lectins, Molecular modeling, Proteins, Supramolecular chemistry",

author = "Nir Dotan and Dorit Arad and Felix Frolow and Amihay Freeman",

year = "1999",

month = aug,

day = "12",

doi = "10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D",

language = "אנגלית",

volume = "38",

pages = "2363--2366",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "16",

}

TY - JOUR

T1 - Self-assembly of a tetrahedral lectin into predesigned diamondlike protein crystals

AU - Dotan, Nir

AU - Arad, Dorit

AU - Frolow, Felix

AU - Freeman, Amihay

PY - 1999/8/12

Y1 - 1999/8/12

N2 - Binding sites analogous to those of sp3 carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C2 spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.

AB - Binding sites analogous to those of sp3 carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C2 spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.

KW - Crystal engineering

KW - Lectins

KW - Molecular modeling

KW - Proteins

KW - Supramolecular chemistry

UR - http://www.scopus.com/inward/record.url?scp=0033549738&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D

DO - 10.1002/(SICI)1521-3773(19990816)38:16<2363::AID-ANIE2363>3.0.CO;2-D

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0033549738

VL - 38

SP - 2363

EP - 2366

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 16

ER -

Self-assembly of a tetrahedral lectin into predesigned diamondlike protein crystals

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this