Selective attachment of multiple cell types on thermally responsive polymer

Yanbing Wang, Xuanhong Cheng, Y. Hanein, A. Shastry, D. D. Denton, B. D. Ratner, K. F. Böhringer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations

Abstract

Programmable surface chemistry has been achieved by depositing a temperature sensitive polymer onto arrays of micro-fabricated metallic heaters. Activating a single heater causes a localized change in the device surface chemistry from non-fouling to fouling in an aqueous environment. Two types of proteins and two types of cells were used to demonstrate localized immobilization of proteins and cells on such surface. These experiments show, for the first time, selective cell attachments on thermally responsive polymer controlled by a micro heater array. It suggests a new approach to realize proteomic chips and cell chips.

Original languageEnglish
Title of host publicationTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages979-982
Number of pages4
ISBN (Electronic)0780377311, 9780780377318
DOIs
StatePublished - 2003
Externally publishedYes
Event12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers - Boston, United States
Duration: 8 Jun 200312 Jun 2003

Publication series

NameTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
Volume2

Conference

Conference12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers
Country/TerritoryUnited States
CityBoston
Period8/06/0312/06/03

Funding

FundersFunder number
National Science Foundation

    Keywords

    • Chemical technology
    • Chemistry
    • Fabrication
    • Glass
    • Liquid crystal polymers
    • Paints
    • Proteins
    • Sensor arrays
    • Switches
    • Temperature sensors

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