Selective Aryl-Fluoride Reductive Elimination from a Platinum(IV) Complex

Ina Dubinsky-Davidchik; Israel Goldberg; Arkadi Vigalok; Andrei N. Vedernikov

doi:10.1002/anie.201503116

Selective Aryl-Fluoride Reductive Elimination from a Platinum(IV) Complex

Ina Dubinsky-Davidchik, Israel Goldberg, Arkadi Vigalok^*, Andrei N. Vedernikov

^*Corresponding author for this work

School of Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

A difluoro(mesityl)platinum(IV) complex underwent highly selective reductive elimination of 2-fluoromesitylene upon heating in toluene. Kinetic analysis and DFT calculations suggest that the C-F coupling involves a five-coordinate Pt^IV transient intermediate resulting from the rate-limiting dissociation of the pyridine ligand.

Original language	English
Pages (from-to)	12447-12451
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	54
Issue number	42
DOIs	https://doi.org/10.1002/anie.201503116
State	Published - 1 Oct 2015

Keywords

chemoselectivity
electrophilic fluorination
platinum
reaction mechanisms
reductive elimination

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10.1002/anie.201503116

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abstract = "A difluoro(mesityl)platinum(IV) complex underwent highly selective reductive elimination of 2-fluoromesitylene upon heating in toluene. Kinetic analysis and DFT calculations suggest that the C-F coupling involves a five-coordinate PtIV transient intermediate resulting from the rate-limiting dissociation of the pyridine ligand.",

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AU - Vedernikov, Andrei N.

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AB - A difluoro(mesityl)platinum(IV) complex underwent highly selective reductive elimination of 2-fluoromesitylene upon heating in toluene. Kinetic analysis and DFT calculations suggest that the C-F coupling involves a five-coordinate PtIV transient intermediate resulting from the rate-limiting dissociation of the pyridine ligand.

KW - chemoselectivity

KW - electrophilic fluorination

KW - platinum

KW - reaction mechanisms

KW - reductive elimination

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Selective Aryl-Fluoride Reductive Elimination from a Platinum(IV) Complex

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