Sedation effect on temporary threshold shift induced by acoustic overstimulation

Minka Hildesheimer; Yael Henkin; Chava Muchnik; Rachel Anafi; Emma Sahartov; Moshe Rubinstein

doi:10.1016/0378-5955(91)90014-Z

Sedation effect on temporary threshold shift induced by acoustic overstimulation

Minka Hildesheimer^*, Yael Henkin, Chava Muchnik, Rachel Anafi, Emma Sahartov, Moshe Rubinstein

^*Corresponding author for this work

Department of Communication Disorders

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The mechanism by which noise damages the inner ear has not as yet been fully elucidated. Experiments were done to study the influence of the sedation in temporary threshold shift (TS) induced by acoustic overstimulation, as barbiturates were found to improve the brain's tolerance to ischemia. Four groups of guinea pigs (GP) were used. The temporary TS was decreased with the reduction of the temperature in awake, as well as sedated, sound-exposed GP. However, the temporary TS in the sedated, but normothermic GP was as great as in the awake, normothermic group. The high temperature counteracts the protection effect of the sedation in noise-induced hearing loss.

Original language	English
Pages (from-to)	161-166
Number of pages	6
Journal	Hearing Research
Volume	51
Issue number	1
DOIs	https://doi.org/10.1016/0378-5955(91)90014-Z
State	Published - Jan 1991

Keywords

Sedation
Temperature
Temporary threshold shift

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abstract = "The mechanism by which noise damages the inner ear has not as yet been fully elucidated. Experiments were done to study the influence of the sedation in temporary threshold shift (TS) induced by acoustic overstimulation, as barbiturates were found to improve the brain's tolerance to ischemia. Four groups of guinea pigs (GP) were used. The temporary TS was decreased with the reduction of the temperature in awake, as well as sedated, sound-exposed GP. However, the temporary TS in the sedated, but normothermic GP was as great as in the awake, normothermic group. The high temperature counteracts the protection effect of the sedation in noise-induced hearing loss.",

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AU - Sahartov, Emma

AU - Rubinstein, Moshe

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AB - The mechanism by which noise damages the inner ear has not as yet been fully elucidated. Experiments were done to study the influence of the sedation in temporary threshold shift (TS) induced by acoustic overstimulation, as barbiturates were found to improve the brain's tolerance to ischemia. Four groups of guinea pigs (GP) were used. The temporary TS was decreased with the reduction of the temperature in awake, as well as sedated, sound-exposed GP. However, the temporary TS in the sedated, but normothermic GP was as great as in the awake, normothermic group. The high temperature counteracts the protection effect of the sedation in noise-induced hearing loss.

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Sedation effect on temporary threshold shift induced by acoustic overstimulation

Abstract

Keywords

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