Secular trends in testosterone- findings from a large state-mandate care provider

Gabriel Chodick*, Shdema Epstein, Varda Shalev

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Several studies from the US and Europe have shown a population-level decline in serum testosterone in men from 1970's to early 2000's. However, to the best of our knowledge, no study examining population-level decline in testosterone has been published in more recent years. The study objective was therefore to examine secular trends in testosterone levels among Israeli men in the first and second decades of the twenty-first century, Methods: All incident total testosterone performed between1/2006 and 3/2019 among 102,334 male members of a large health organization. Results: A significant (p < 0.001) and prominent trend of age-independent decline in the testosterone levels was recorded during the study period for most age groups. Conclusions: There was a highly significant age-independent decline in total testosterone in the first and second decades of the twenty-first century. The decline was unlikely to be explained by increasing rates of obesity.

Original languageEnglish
Article number19
JournalReproductive Biology and Endocrinology
Volume18
Issue number1
DOIs
StatePublished - 9 Mar 2020

Keywords

  • Israel
  • Secular trends
  • Testosterone

Fingerprint

Dive into the research topics of 'Secular trends in testosterone- findings from a large state-mandate care provider'. Together they form a unique fingerprint.

Cite this