Seasonality and Autoimmune Diseases

Abdulla Watad; Kassem Sharif; Nicola Luigi Bragazzi; Benjamin Lichtbroun; Howard Amital; Yehuda Shoenfeld

doi:10.1016/B978-0-12-814307-0.00023-2

Seasonality and Autoimmune Diseases

Abdulla Watad^*, Kassem Sharif, Nicola Luigi Bragazzi, Benjamin Lichtbroun, Howard Amital, Yehuda Shoenfeld

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Autoimmune diseases result from the loss of tolerance to self-tissues. Large strides have been made in elucidating the complex immunologic background of such diseases. The interplay of genetic, epigenetic, and environmental factors shifted our understanding of disease etiopathogenesis. The seasonal variation of various environmental factors is demonstrated to play a contributory role in disease induction and progression. Such factors include vitamin D, ultraviolet radiation, melatonin, and infections. In this chapter, the effect of seasonality on autoimmune diseases is discussed. The consideration of such factors provides an avenue for further research into new treatment and preventive measures.

Original language	English
Title of host publication	Mosaic of Autoimmunity
Subtitle of host publication	The Novel Factors of Autoimmune Diseases
Publisher	Elsevier
Pages	229-234
Number of pages	6
ISBN (Electronic)	9780128143087
ISBN (Print)	9780128143070
DOIs	https://doi.org/10.1016/B978-0-12-814307-0.00023-2
State	Published - 13 Feb 2019

Keywords

Autoimmune diseases
Infections
Month of birth
Seasonality
Vitamin D

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10.1016/B978-0-12-814307-0.00023-2

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AU - Shoenfeld, Yehuda

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Seasonality and Autoimmune Diseases

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Keywords

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