Screening for colorectal cancer and polyps

Y. Krieger, D. Fraser, H. S. Odes, P. Krugliak, G. M. Fraser

Research output: Contribution to journalArticlepeer-review

Abstract

Screening programs for the early detection of colorectal neoplasms may prevent cancer or improve its prognosis. We screened 1101 individuals (89% of whom were asymptomatic) using 3 methods. The fecal occult blood test, done in 96% of those screened, was positive in only 1.9% and was low in both sensitivity (2.1%) and positive predictive value (6.7%). However, flexible sigmoidoscopy, performed in 48%, gave positive results in 7.8% of those screened, revealing 41 cases of polyps and 1 of cancer. Colonoscopy was performed in 8% and 37 cases of polyps and 1 of cancer were detected. Of the 3 screening methods tested, sigmoidoscopy appeared to be the best because of its high diagnostic yield. The risk of colorectal neoplasm was shown for the first time to be equal in Jews of oriental and occidental origin.

Original languageEnglish
Pages (from-to)354-356, 408
JournalHarefuah
Volume122
Issue number6
StatePublished - 15 Mar 1992
Externally publishedYes

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