Screening and diagnosis of gestational diabetes mellitus: Critical appraisal of the new International Association of Diabetes in Pregnancy Study Group recommendations on a national level

Ofra Kalter-Leibovici, Orna Tal, Laurence S. Freedman, Liat Lerner-Geva, Liraz Olmer, Nir Melamed, Nicky Liebermann, Moshe Hod, Anthony Heymann

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE - To study the implications of implementing the International Association of Diabetes in Pregnancy Study Group (IADPSG) recommendations for screening and diagnosis of gestational diabetes mellitus (GDM) in Israel and explore alternative methods for identifying women at risk for adverse pregnancy outcomes. RESEARCH DESIGN AND METHODS - We analyzed data of the Israeli Hyperglycemia and Adverse Pregnancy Outcomes study participants (N = 3,345). Adverse outcome rates were calculated and compared for women who were positive according to 1) IADPSG criteria, 2) IADPSG criteria with risk stratification, or 3) screening with BMI or fasting plasma glucose (FPG). RESULTS - Adopting IADPSG recommendations would increase GDM diagnosis by ∼50%. One-third of IADPSG-positive women were at low risk for adverse outcomes and could be managed less intensively. FPG ≥89 mg/dL or BMI ≥33.5 kg/m2 at 28-32 weeks of gestation detected proportions of adverse outcomes similar to IADPSG criteria. CONCLUSIONS - Implementing IADPSG recommendations will substantially increase GDM diagnosis. Risk stratification in IADPSG-positive women may reduce over-treatment. Screening with FPG or BMI may be a practical alternative.

Original languageEnglish
Pages (from-to)1894-1896
Number of pages3
JournalDiabetes Care
Volume35
Issue number9
DOIs
StatePublished - Sep 2012

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