Sarcoglane, a new cytotoxic diterpene from Sarcophyton glaucum

Einat Fridkovsky, Amira Rudi, Yehuda Benayahu, Yoel Kashman, Michael Schleyer

Research output: Contribution to journalArticlepeer-review


Sarcoglane (1) a new tricyclo[7,5,010,14]tetradecane diterpenoid has been isolated from the Indo-Pacific soft coral Sarcophyton glaucum. The structure of compound 1, which is cytotoxic to fertilized sea urchin eggs, was defined by spectral methods and mainly 1D and 2D NMR experiments. Sarcoglane possesses an unprecedented tricyclic carbon skeleton, biogenetically, closely related to the membrane and xeniaphyllane diterpenoids.

Original languageEnglish
Pages (from-to)6909-6910
Number of pages2
JournalTetrahedron Letters
Issue number38
StatePublished - 16 Sep 1996


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